Anti-PRPF19 Rabbit Monoclonal Antibody
Catalog No.
MA4758
Anti-PRPF19 Rabbit Monoclonal Antibody
Featured Products
Ubiquitin-protein ligase which is a core component of several complexes mainly involved pre-mRNA splicing and DNA repair. Core component of the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity. During assembly of the spliceosome, mediates 'Lys-63'-linked polyubiquitination of the U4 spliceosomal protein PRPF3. Ubiquitination of PRPF3 allows its recognition by the U5 component PRPF8 and stabilizes the U4/U5/U6 tri-snRNP spliceosomal complex (PubMed:20595234).
27339
PRPF19; NMP200; PRP19; SNEV; Pre-mRNA-processing factor 19; Nuclear matrix protein 200; PRP19/PSO4 homolog; hPso4; Senescence evasion factor
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 55 kDa; Observed MW: 55 kDa
Unmodified
IgG
Monoclonal Antibody
AP-12H1E5
Liquid
See label
Carrier Free
A synthesized peptide derived from human PRP19
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IHC-P, ICC/IF, FC
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.