Anti-PRAS40 Rabbit Monoclonal Antibody
Catalog No.
MA4707
Anti-PRAS40 Rabbit Monoclonal Antibody
Featured Products
PRAS40 interacts with Raptor in mTOR complex 1 (mTORC1) in insulin-deprived cells and inhibits the activation of the mTORC1 pathway mediated by the cell cycle protein Rheb. Phosphorylation of PRAS40 by Akt at Thr246 relieves PRAS40 inhibition of mTORC1. mTORC1 in turn phosphorylates PRAS40 at Ser183.
84335
AKT1S1; PRAS40; Proline-rich AKT1 substrate 1; 40 kDa proline-rich AKT substrate
Rabbit
Human, Rat
Unconjugated
Calculated MW: 27 kDa; Observed MW: 40 kDa
Unmodified
IgG
Monoclonal Antibody
AP-6A6F3
Liquid
See label
Carrier Not Free
A synthetic peptide of human PRAS40
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.