Anti-PRAS40 Rabbit Monoclonal Antibody
Catalog No.
MA4709
Anti-PRAS40 Rabbit Monoclonal Antibody
Featured Products
PRAS40 interacts with Raptor in mTOR complex 1 (mTORC1) in insulin-deprived cells and inhibits the activation of the mTORC1 pathway mediated by the cell cycle protein Rheb. Phosphorylation of PRAS40 by Akt at Thr246 relieves PRAS40 inhibition of mTORC1. mTORC1 in turn phosphorylates PRAS40 at Ser183.
84335
AKT1S1; PRAS40; Proline-rich AKT1 substrate 1; 40 kDa proline-rich AKT substrate
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 27 kDa; Observed MW: 40 kDa
Unmodified
IgG
Monoclonal Antibody
AP-3E6A11
Liquid
See label
Carrier Free
A synthesized peptide derived from human PRAS40
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.