Anti-PI3 Kinase p85 alpha (1C8) Mouse Monoclonal Antibody
Catalog No.
MA4586
Anti-PI3 Kinase p85 alpha (1C8) Mouse Monoclonal Antibody
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Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.
5295
PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha
Mouse
Human, Mouse, Rat
Unconjugated
Calculated MW: 84 kDa; Observed MW: 84 kDa
Unmodified
IgG1
Monoclonal Antibody
AP-11F3E11
Liquid
See label
Carrier Not Free
Purified recombinant protein expressed in E.coli.
Affinity Purified
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
WB, IHC-P
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.