Anti-Phospho-SMC1A (Ser957) Rabbit Monoclonal Antibody
Catalog No.
MA4546
Anti-Phospho-SMC1A (Ser957) Rabbit Monoclonal Antibody
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Structural maintenance of chromosomes 1 (SMC1) protein is a chromosomal protein member of the cohesin complex that enables sister chromatid cohesion and plays a role in DNA repair . ATM/NBS1-dependent phosphorylation of SMC1 occurs at Ser957 and Ser966 in response to ionizing radiation (IR) as part of the intra-S-phase DNA damage checkpoint. SMC1 phosphorylation is ATM-independent in cells subjected to other forms of DNA damage, including UV light and hydroxyurea treatment.
8243
Chromosome segregation protein SmcB; DXS423E; KIAA0178; MGC138332; Sb1.8; Segregation of mitotic chromosomes 1; SMC protein 1A; SMC-1-alpha; SMC-1A; SMC1 (structural maintenance of chromosomes 1 yeast) like 1; SMC1; SMC1 structural maintenance of chromosomes 1 like 1; SMC1A; SMC1A_HUMAN; SMC1alpha; SMC1L1; SMCB; Structural maintenance of chromosomes 1A; Structural maintenance of chromosomes protein 1A.
Rabbit
Human
Unconjugated
Calculated MW: 143 kDa; Observed MW: 160 kDa
Phosphorylated
IgG
Monoclonal Antibody
AP-15H12C2
Liquid
See label
Carrier Free
A synthesized peptide derived from human Phospho-SMC1 (S957)
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IHC-P, ICC/IF
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.