Anti-Phospho-Rb (Ser780) Rabbit Monoclonal Antibody
Catalog No.
MA4516
Anti-Phospho-Rb (Ser780) Rabbit Monoclonal Antibody
Featured Products
Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression. Rb inactivation and subsequent cell cycle progression likely requires an initial phosphorylation by cyclin D-CDK4/6 followed by cyclin E-CDK2 phosphorylation. Specificity of different CDK/cyclin complexes has been observed in vitro and cyclin D1 is required for Ser780 phosphorylation in vivo.
5925
RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110
Rabbit
Human, Rat
Unconjugated
Calculated MW: 106 kDa; Observed MW: 110 kDa
Phosphorylated
IgG
Monoclonal Antibody
AP-18F7D2
Liquid
See label
Carrier Not Free
A synthetic phosphopeptide corresponding to residues surrounding Ser780 of human Rb
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.