Anti-Phospho-Raf1 (Ser259) Rabbit Monoclonal Antibody
Catalog No.
MA4512
Anti-Phospho-Raf1 (Ser259) Rabbit Monoclonal Antibody
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Raf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2.
5894
RAF1; RAF; RAF proto-oncogene serine/threonine-protein kinase; Proto-oncogene c-RAF; cRaf; Raf-1
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 73 kDa; Observed MW: 73 kDa
Phosphorylated
IgG
Monoclonal Antibody
AP-12H7A4
Liquid
See label
Carrier Not Free
A synthetic phosphopeptide corresponding to residues surrounding Ser259 of human Raf1
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB, IHC-P
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.