Anti-Phospho-Phospholamban (Ser16) Rabbit Monoclonal Antibody
Catalog No.
MA4487
Anti-Phospho-Phospholamban (Ser16) Rabbit Monoclonal Antibody
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Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca2+. Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation.
5350
PLN; PLB; Cardiac phospholamban; PLB
Rabbit
Human, Mouse
Unconjugated
Calculated MW: 6 kDa; Observed MW: 12,24 kDa
Phosphorylated
IgG
Monoclonal Antibody
AP-12B1G2
Liquid
See label
Carrier Not Free
A synthetic phosphopeptide corresponding to residues surrounding Ser16 of human Phospholamban
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.