Anti-Phospho-JAK2 (Tyr1007/1008) Rabbit Monoclonal Antibody
Catalog No.
MA4436
Anti-Phospho-JAK2 (Tyr1007/1008) Rabbit Monoclonal Antibody
Featured Products
Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2.
3717
JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 131 kDa; Observed MW: 131 kDa
Phosphorylated
IgG
Monoclonal Antibody
AP-16G7B7
Liquid
See label
Carrier Free
A synthesized peptide derived from human Phospho-JAK2 (Y1007 + Y1008)
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IHC-P, ICC/IF, FC, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.