Anti-Phospho-IRE1 (Ser724) Rabbit Monoclonal Antibody
Catalog No.
MA4433
Anti-Phospho-IRE1 (Ser724) Rabbit Monoclonal Antibody
Featured Products
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
2081
ERN1; IRE1; Serine/threonine-protein kinase/endoribonuclease IRE1; Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1; hIRE1p; Ire1-alpha; IRE1a
Rabbit
Human
Unconjugated
Calculated MW: 110 kDa; Observed MW: 110 kDa
Phosphorylated
IgG
Monoclonal Antibody
AP-20D11E2
Liquid
See label
Carrier Not Free
A synthetic phosphopeptide corresponding to residues surrounding Ser724 of human IRE1
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.