Anti-Phospho-FOXO3A (Ser253) Rabbit Monoclonal Antibody
Catalog No.
MA4404
Anti-Phospho-FOXO3A (Ser253) Rabbit Monoclonal Antibody
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FoxO3a is a transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
2309
FOXO3; FKHRL1; FOXO3A; Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 71 kDa; Observed MW: 82 kDa
Phosphorylated
IgG
Monoclonal Antibody
AP-19B7D12
Liquid
See label
Carrier Not Free
A synthetic phosphopeptide corresponding to residues surrounding Ser253 of human FOXO3A
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.