Anti-Phospho-FGFR1 (Tyr654) Rabbit Polyclonal Antibody
Catalog No.
PA1279
Anti-Phospho-FGFR1 (Tyr654) Rabbit Polyclonal Antibody
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Fibroblast growth factors (FGFs) produce mitogenic and angiogenic effects in target cells by signaling through cell surface receptor tyrosine kinases. Each receptor contains an extracellular ligand binding domain, a transmembrane domain, and a cytoplasmic kinase domain. Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues. Seven tyrosine residues in the cytoplasmic tail of FGFR1 can be phosphorylated: Tyr463, 583, 585, 653, 654, 730, and 766.
2260
FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR; Fibroblast growth factor receptor 1; FGFR-1; Basic fibroblast growth factor receptor 1; BFGFR; bFGF-R-1; Fms-like tyrosine kinase 2; FLT-2; N-sam; Proto-oncogene c-Fgr; CD antigen CD331
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 92 kDa; Observed MW: 120 kDa
Phosphorylated
IgG
Polyclonal Antibody
Liquid
See label
Carrier Not Free
The antiserum was produced against synthesized peptide derived from human FGFR1 around the phosphorylation site of Tyr654.
Affinity Chromatography
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
WB, ICC/IF, ELISA
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.