Anti-Phospho-CRK (Tyr221) Rabbit Monoclonal Antibody
Catalog No.
MA4371
Anti-Phospho-CRK (Tyr221) Rabbit Monoclonal Antibody
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The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
1398
Adapter molecule crk; avian sarcoma virus CT10 (v-crk) oncogene homolog; CRK; CRKII; Proto-oncogene c-Crk
Rabbit
Human
Unconjugated
Calculated MW: 34 kDa; Observed MW: 42 kDa
Phosphorylated
IgG
Monoclonal Antibody
AP-13D2E9
Liquid
See label
Carrier Free
A synthesized peptide derived from human Phospho-CrkII (Tyr221)
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, ICC/IF
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.