Anti-Phospho-Chk2 (Thr68) Rabbit Polyclonal Antibody
Catalog No.
PA1275
Anti-Phospho-Chk2 (Thr68) Rabbit Polyclonal Antibody
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These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function.
11200
CHEK2; CDS1; CHK2; RAD53; Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 61 kDa; Observed MW: 61 kDa
Phosphorylated
IgG
Polyclonal Antibody
Liquid
See label
Carrier Not Free
The antiserum was produced against synthesized peptide derived from human Chk2 around the phosphorylation site of Thr68.
Affinity Purified
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
WB, IHC-P, ICC/IF
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.