Anti-Phospho-CDC6 (Ser106) Rabbit Monoclonal Antibody
Catalog No.
MA4358
Anti-Phospho-CDC6 (Ser106) Rabbit Monoclonal Antibody
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Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.Cdc6 has recently been shown to play an important role in the intra-S-phase p21 Waf1/Cip1-dependent DNA damage response. Both cdc6 and CDT1 are degraded by the ubiquitin proteasome pathway in response to DNA damage associated with re-replication.
990
CDC6; CDC18L; Cell division control protein 6 homolog; CDC6-related protein; Cdc18-related protein; HsCdc18; p62(cdc6); HsCDC6
Rabbit
Human, Rat
Unconjugated
Calculated MW: 63 kDa; Observed MW: 63 kDa
Phosphorylated
IgG
Monoclonal Antibody
AP-15A3A7
Liquid
See label
Carrier Not Free
A synthetic phosphopeptide corresponding to residues surrounding Ser106 of human Cdc6
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.