Anti-Phospho-AKT (Ser473) Rabbit Monoclonal Antibody
Catalog No.
MA4327
Anti-Phospho-AKT (Ser473) Rabbit Monoclonal Antibody
Featured Products
Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.
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AKT1; PKB; RAC; RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 56 kDa; Observed MW: 56 kDa
Phosphorylated
IgG
Monoclonal Antibody
AP-8B2G12
Liquid
See label
Carrier Not Free
A synthetic phosphopeptide corresponding to residues surrounding Ser473 of human AKT1
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.