Anti-PHD2 Rabbit Monoclonal Antibody
Catalog No.
MA4319
Anti-PHD2 Rabbit Monoclonal Antibody
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Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-402' and 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
54583
EGLN1; C1orf12; ECYT3; HIFPH2; HPH2; PHD2; SM-20; SM20; ZMYND6; PHD2
Rabbit
Human
Unconjugated
Calculated MW: 46 kDa; Observed MW: 46 kDa
Unmodified
IgG
Monoclonal Antibody
AP-8G7C1
Liquid
See label
Carrier Free
A synthesized peptide derived from human PHD2 / prolyl hydroxylase
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.