Anti-PHD1 Rabbit Monoclonal Antibody
Catalog No.
MA4318
Anti-PHD1 Rabbit Monoclonal Antibody
Featured Products
Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF2A. Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
112398
Estrogen-induced tag 6; HPH-3; PHD1
Rabbit
Human, Rat
Unconjugated
Calculated MW: 44 kDa; Observed MW: 44 kDa
Unmodified
IgG
Monoclonal Antibody
AP-17E8B9
Liquid
See label
Carrier Not Free
A synthesized peptide derived from human PHD1/prolyl hydroxylase
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.