Anti-Notch4 Rabbit Monoclonal Antibody
Catalog No.
MA4022
Anti-Notch4 Rabbit Monoclonal Antibody
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Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity).
4855
NOTCH4; INT3; Neurogenic locus notch homolog protein 4; Notch 4; hNotch4
Rabbit
Human
Unconjugated
Calculated MW: 210 kDa; Observed MW: 36 kDa
Unmodified
IgG
Monoclonal Antibody
AP-4B11H3
Liquid
See label
Carrier Not Free
A synthetic peptide of human NOTCH4
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.