Anti-Notch1 Rabbit Monoclonal Antibody
Catalog No.
MA4020
Anti-Notch1 Rabbit Monoclonal Antibody
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Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting.
4851
NOTCH1; TAN1; Neurogenic locus notch homolog protein 1; Notch 1; hN1; Translocation-associated notch protein TAN-1
Rabbit
Human, Rat
Unconjugated
Calculated MW: 273 kDa; Observed MW: 120 kDa
Unmodified
IgG
Monoclonal Antibody
AP-8C12C1
Liquid
See label
Carrier Not Free
A synthetic peptide of human Notch1
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.