Anti-Notch1 Rabbit Monoclonal Antibody
Catalog No.
MA4021
Anti-Notch1 Rabbit Monoclonal Antibody
Featured Products
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting.
4851
NOTCH1; TAN1; Neurogenic locus notch homolog protein 1; Notch 1; hN1; Translocation-associated notch protein TAN-1
Rabbit
Human, Mouse
Unconjugated
Calculated MW: 273 kDa
Unmodified
IgG
Monoclonal Antibody
AP-10G9C10
Liquid
See label
Carrier Free
A synthesized peptide derived from human Notch1
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IHC-P, ICC/IF, FC
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.