Anti- Mouse B7-H1/PD-L1 (Clone 10F.9G2) In Vivo Mab
Anti-Mouse B7-H1/PD-L1 (Clone 10F.9G2) In Vivo Mab is a rat host-derived anti-mouse PD-L1/B7-H1 (Rat IgG2b) antibody inhibitor. It functions by binding to mouse PD-L1 (also known as B7-H1 or CD274) to block the interactions between PD-L1 and PD-1, as well as between PD-L1 and B7-1 (CD80). This antibody has important applications in cancer research, such as in studies of colon cancer.
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Alternative Names |
B7-H1, CD274; Recombinant mouse PD-L1 neutralizing monoclonal antibody |
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Target Accession |
Q9EP73 |
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Target |
B7-H1 / PD-L1 / CD274 |
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Molecular Weight |
150 kDa |
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Host |
CHO |
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Reactivity |
Mouse |
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Conjugation |
Unconjugated |
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Form |
Liquid |
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Concentration |
See label |
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Buffer System |
100mM Pro-Ac, 20mM Arg pH 5.0 Lyophilization: 25mM histidine, 8% sucrose, 0.01% Tween80 pH6.2 |
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Clonality |
Monoclonal |
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Purification |
Protein A |
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Isotype |
Rat IgG2b |
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Application |
ELISA, Kinetics (SPR), WB, IHC, FCM, Block, In Vivo |
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Biological activity |
ELISA assay: Immobilized mouse PD-L1 (FC Tag, 2μg/mL) can bind to Anti- Mouse B7-H1/PD-L1 (Clone 10F.9G2) In Vivo Mab with an EC50 of 0.03045 μg/mL. |
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Endotoxin |
Less than 1 EU/mg determined by LAL method. |
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Sterilization |
0.2 μm Filtered |
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Reconstitution |
For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex. |
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Shipping |
dry ice |
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Storage |
-80oC |
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Expiration Date |
2 years |
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Note |
Please avoid freeze-thaw cycles. |
Quality Control & DataSheet
- View current batch:
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Purity > 95% by SDS-PAGE and SEC-HPLC analyses.
- Datasheet