Anti-MAGEA3 Rabbit Monoclonal Antibody
Catalog No.
MA3587
Anti-MAGEA3 Rabbit Monoclonal Antibody
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Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
4102
HIP8; HYPD; CT1.3; MAGE3; MAGEA6
Rabbit
Human
Unconjugated
Calculated MW: 35 kDa; Observed MW: 45 kDa
Unmodified
IgG
Monoclonal Antibody
AP-11E6D8
Liquid
See label
Carrier Not Free
Recombinant protein of human MAGEA3
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.