Anti-LRRK2 Rabbit Monoclonal Antibody
Catalog No.
MA3551
Anti-LRRK2 Rabbit Monoclonal Antibody
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Positively regulates autophagy through a calcium-dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner.
120892
AURA17; Dardarin antibody; ; Leucine rich repeat kinase 2; LRRK 2 antibody; LRRK2; LRRK2_HUMAN; PARK 8; PARK8; RIPK7; ROCO 2; ROCO2
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 286 kDa; Observed MW: 280 kDa
Unmodified
IgG
Monoclonal Antibody
AP-15B4G4
Liquid
See label
Carrier Free
A synthesized peptide derived from human LRRK2
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IHC-P, ICC/IF, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.