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Anti-LILRB2/ILT4/CD85d Antibody (JTX-8064)

Catalog No.
F1477
Anti-LILRB2/ILT4/CD85d Antibody (JTX-8064)
Grouped product items
SizePriceStock Qty
100ug
$90.00
Ship with 3-5 days
1mg
$270.00
Ship with 3-5 days
5mg
$756.00
Ship with 3-5 days
50mg
$2,533.00
Ship with 3-5 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Polzastobart (JTX-8064) is a humanizedIgG4 monoclonal antagonist antibody that selectively binds to LILRB2 and prevents its binding to ligands, classical and non-classical MHC I molecules. Polzastobart enhances the production of pro-inflammatory cytokines in macrophages by blocking the ability of LILRB2 to bind to HLA-A/B and/or HLA-G (cancer cell immune tolerance markers). Polzastobart is a macrophage immune checkpoint inhibitor.

Quality Control

Quality Control & DataSheet

View current batch:
 

M.Wt

145 kDa

Shipping

Dry ice

Cas No.

2640981-19-5

Storage

-80°C

Expiration Date

2 years

Form

Liquid

Concentration

See label

Reconstitution

For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.

Host

CHO

Alternative Names

Polzastobart

Buffer System

100 mM Pro 20 mM Arg pH 5.0. No preservative!

Target Accession

Q8N423

Reactivity

Human

Conjugation

Unconjugated

Clonality

Monoclonal

Purification

Protein A

Isotype

IgG4

Application

ELISA, FACS, Kinetics, Functional assay, Animal Model

Biological Activity

Immobilized human LILRB2 His at 2 ug/mL can bind Anti-LILRB2/ILT4/CD85d Antibody (JTX-8064)

Target

LILRB2 / ILT4 / CD85d

Note

Please avoid freeze-thaw cycles.