Anti-LGR5 Rabbit Monoclonal Antibody
Catalog No.
MA3495
Anti-LGR5 Rabbit Monoclonal Antibody
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Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes.
8549
FEX; GPR49; GPR67; GRP49; LGR5; HG38; 8
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 100 kDa; Observed MW: 100 kDa
Unmodified
IgG
Monoclonal Antibody
AP-6D3B10
Liquid
See label
Carrier Free
A synthesized peptide derived from human LGR5/GPR49
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, FC, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.