Anti-LAT Rabbit Polyclonal Antibody
Catalog No.
PA1194
Anti-LAT Rabbit Polyclonal Antibody
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Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
27040
LAT; Linker for activation of T-cells family member 1; 36 kDa phospho-tyrosine adapter protein; pp36; p36-38
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 28 kDa; Observed MW: 28 kDa
Unmodified
IgG
Polyclonal Antibody
Liquid
See label
Carrier Not Free
Synthesized peptide derived from LAT.
Affinity Purified
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
WB, ELISA
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.