Anti-KCTD21 Rabbit Monoclonal Antibody
Catalog No.
MA3388
Anti-KCTD21 Rabbit Monoclonal Antibody
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Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB) (PubMed:21472142).
283219
KCASH2
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 30 kDa; Observed MW: 30 kDa
Unmodified
IgG
Monoclonal Antibody
AP-12F6F11
Liquid
See label
Carrier Not Free
Recombinant protein of human KCTD21
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.