Anti-ITCH Rabbit Monoclonal Antibody
Catalog No.
MA3340
Anti-ITCH Rabbit Monoclonal Antibody
Featured Products
Involved in the negative regulation of MAVS-dependent cellular antiviral responses. Ubiquitinates MAVS through 'Lys-48'-linked conjugation resulting in MAVS proteosomal degradation. Involved in the regulation of apoptosis and reactive oxygen species levels through the ubiquitination and proteosomal degradation of TXNIP. Mediates the antiapoptotic activity of epidermal growth factor through the ubiquitination and proteosomal degradation of p15 BID.
83737
ITCH; E3 ubiquitin-protein ligase Itchy homolog; Itch; Atrophin-1-interacting protein 4; AIP4; NFE2-associated polypeptide 1; NAPP1
Rabbit
Human
Unconjugated
Calculated MW: 103 kDa; Observed MW: 103 kDa
Unmodified
IgG
Monoclonal Antibody
AP-1F4H7
Liquid
See label
Carrier Not Free
A synthetic peptide of human ITCH/AIP4
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.