Anti-ITCH Rabbit Monoclonal Antibody
Catalog No.
MA3342
Anti-ITCH Rabbit Monoclonal Antibody
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Involved in the negative regulation of MAVS-dependent cellular antiviral responses. Ubiquitinates MAVS through 'Lys-48'-linked conjugation resulting in MAVS proteosomal degradation. Involved in the regulation of apoptosis and reactive oxygen species levels through the ubiquitination and proteosomal degradation of TXNIP. Mediates the antiapoptotic activity of epidermal growth factor through the ubiquitination and proteosomal degradation of p15 BID.
83737
ITCH; E3 ubiquitin-protein ligase Itchy homolog; Itch; Atrophin-1-interacting protein 4; AIP4; NFE2-associated polypeptide 1; NAPP1
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 103 kDa; Observed MW: 103 kDa
Unmodified
IgG
Monoclonal Antibody
AP-14G3E3
Liquid
See label
Carrier Free
A synthesized peptide derived from human ITCH
Affinity Purified
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IHC-P
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.