Anti-IRF1 Rabbit Monoclonal Antibody
Catalog No.
MA3323
Anti-IRF1 Rabbit Monoclonal Antibody
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Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Acts as a tumor suppressor. Defects in IRF1 are a cause of gastric cancer (GASC) [MIM:613659]; also called gastric cancer intestinal or stomach cancer. Gastric cancer is a malignant disease which starts in the stomach, can spread to the esophagus or the small intestine, and can extend through the stomach wall to nearby lymph nodes and organs. It also can metastasize to other parts of the body.
3659
IRF1; Interferon regulatory factor 1; IRF-1
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 37 kDa; Observed MW: 48 kDa
Unmodified
IgG
Monoclonal Antibody
AP-3H5A2
Liquid
See label
Carrier Not Free
Recombinant protein of human IRF1
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB, IHC-F, IHC-P, ICC/IF, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.