Anti-Integrin beta 3 Rabbit Monoclonal Antibody
Catalog No.
MA3290
Anti-Integrin beta 3 Rabbit Monoclonal Antibody
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Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. Fibrinogen binding enhances SELP expression in activated platelets (By similarity).
3690
ITGB3; GP3A; Integrin beta-3; Platelet membrane glycoprotein IIIa; GPIIIa; CD antigen CD61
Rabbit
Human, Mouse
Unconjugated
Calculated MW: 87 kDa; Observed MW: 100 kDa
Unmodified
IgG
Monoclonal Antibody
AP-6A11D9
Liquid
See label
Carrier Not Free
Recombinant protein of human Integrin beta 3
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.