Anti-Integrin beta 3 (3C12) Mouse Monoclonal Antibody
Catalog No.
MA3289
Anti-Integrin beta 3 (3C12) Mouse Monoclonal Antibody
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Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. Fibrinogen binding enhances SELP expression in activated platelets (By similarity).
3690
ITGB3; GP3A; Integrin beta-3; Platelet membrane glycoprotein IIIa; GPIIIa; CD antigen CD61
Mouse
Human
Unconjugated
Calculated MW: 87 kDa; Observed MW: 110 kDa
Unmodified
IgG1
Monoclonal Antibody
AP-20G7A6
Liquid
See label
Carrier Not Free
Purified recombinant human Integrin beta 3(N-terminus) protein fragments expressed in E.coli.
Affinity Purified
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
WB
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.