Anti-IGF1R/CD221 Antibody (Teprotumumab)
Catalog No.
F2073
Anti-IGF1R/CD221 Antibody (Teprotumumab)
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Teprotumumab is a human monoclonal antibody that blocks the IGF-1 receptor (IGF-1R). Teprotumumab binds to the extracellular α-subunit domain ligand of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibroblasts. Teprotumumab reduces TSH-dependent IL-6 and IL-8 expression and Akt phosphorylation. Teprotumumab can be used in the study of thyroid-related eye disease.
Quality Control & DataSheet
- View current batch:
-
Purity > 95% by SDS-PAGE and SEC-HPLC analyses.
- MSDS (Material Safety Data Sheet)
- Datasheet
145.64 kDa
Dry ice
1036734-93-6
-80°C
2 years
Liquid
See label
For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.
CHO
TEPEZZA, RO4858696-000, RO4858696
100 mM Pro 20 mM Arg pH 5.0. No preservative!
P08069
Human, Mouse
Unconjugated
Monoclonal
Protein A
IgG1
ELISA, FACS, Kinetics, Functional assay, Animal Model
Immobilized human IGF1R His at 2 ug/mL can bind Anti-IGF1R/CD221 Antibody (Teprotumumab)
IGF1R / CD221
Please avoid freeze-thaw cycles.