Anti-HP1 alpha (1E8) Mouse Monoclonal Antibody
Catalog No.
MA3093
Anti-HP1 alpha (1E8) Mouse Monoclonal Antibody
Featured Products
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
23468
CBX5; HP1A; Chromobox protein homolog 5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha
Mouse
Human, Rat, Mouse
Unconjugated
Calculated MW: 22 kDa; Observed MW: 22 kDa
Unmodified
IgG1
Monoclonal Antibody
AP-8B5E5
Liquid
See label
Carrier Not Free
Purified recombinant protein expressed in E.coli.
Affinity Purified
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
WB, IHC-P
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.