Anti-HIF1 beta Rabbit Monoclonal Antibody
Catalog No.
MA3002
Anti-HIF1 beta Rabbit Monoclonal Antibody
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HIF-1β is also known as AhR nuclear translocator (ARNT) due to its ability to partner with the aryl hydrocarbon receptor (AhR) to form a heterodimeric transcription factor complex. Together with AhR, HIF-1β plays an important role in xenobiotics metabolism. In addition, a chromosomal translocation leading to a TEL-ARNT fusion protein is associated with acute myeloblastic leukemia. Studies also found that ARNT/HIF-1β expression levels decrease significantly in pancreatic islets from patients with type 2 diabetes, suggesting that HIF-1β plays an important role in pancreatic β-cell function.
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ARNT; BHLHE2; Aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin receptor; nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta
Rabbit
Human
Unconjugated
Calculated MW: 87 kDa; Observed MW: 87 kDa
Unmodified
IgG
Monoclonal Antibody
AP-11G12D7
Liquid
See label
Carrier Free
A synthesized peptide derived from human HIF-1 beta
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IHC-P
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.