Anti-Hamartin Rabbit Monoclonal Antibody
Catalog No.
MA2944
Anti-Hamartin Rabbit Monoclonal Antibody
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In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.
7248
Hamartin; kiaa0243; LAM; TSC; Tsc1; Tuberous sclerosis 1
Rabbit
Human
Unconjugated
Calculated MW: 130 kDa; Observed MW: 150 kDa
Unmodified
IgG
Monoclonal Antibody
AP-20H4B9
Liquid
See label
Carrier Free
A synthesized peptide derived from human Hamartin
Affinity Purified
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IHC-P, ICC/IF, FC
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.