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Anti-GPNMB Antibody (Glembatumumab vedotin)

Catalog No.
F1091
Anti-GPNMB Antibody (Glembatumumab vedotin)
Grouped product items
SizePriceStock Qty
100ug
$140.00
Ship with 3-5 days
1mg
$700.00
Ship with 3-5 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Glembatumumab vedotin (CDX-011) is an ADC (Antibody-Drug Conjugates (ADCs)) consisting of a fully human IgG2 monoclonal antibody (CR011) directed against glycoprotein NMB (GPNMB) and conjugated to the potent tubulin-binding cytotoxic agent MMAE via a protease-sensitive vc linker. Glembatumumab vedotin has potent anticancer effects.

Quality Control

Quality Control & DataSheet

View current batch:
 

M.Wt

145.56 kDa

Shipping

Dry ice

Cas No.

1182215-65-1

Storage

-80°C

Expiration Date

2 years

Form

Liquid

Concentration

See label

Reconstitution

For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.

Host

CHO

Alternative Names

glembatumumab, CR011, CR011-vcMMAE

Buffer System

100 mM Pro 20 mM Arg pH 5.0. No preservative!

Target Accession

Q14956

Reactivity

Human

Conjugation

MMAE

Clonality

Monoclonal

Purification

Protein A

Isotype

IgG2SA

Application

ELISA, FACS, Kinetics, Functional assay, Animal Model

Biological Activity

The drug-to-antibody ratio (DAR) of the Anti-GPNMB Antibody (Glembatumumab vedotin) is 3.6.

Target

GPNMB

Note

Please avoid freeze-thaw cycles.