Anti-GNA13 Rabbit Monoclonal Antibody
Catalog No.
MA2863
Anti-GNA13 Rabbit Monoclonal Antibody
Featured Products
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (PubMed:15240885, PubMed:16787920, PubMed:16705036, PubMed:27084452). Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF1/p115RhoGEF, ARHGEF11/PDZ-RhoGEF and ARHGEF12/LARG) (PubMed:15240885, PubMed:12515866). GNA13-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1) . Promotes tumor cell invasion and metastasis by activating RhoA/ROCK signaling pathway (PubMed:16787920, PubMed:16705036, PubMed:27084452). Inhibits CDH1-mediated cell adhesion in process independent from Rho activation (PubMed:11976333).
10672
guanine nucleotide binding protein (G protein); alpha 13; G13
Rabbit
Human
Unconjugated
Calculated MW: 44 kDa; Observed MW: 44 kDa
Unmodified
IgG
Monoclonal Antibody
AP-6H11B5
Liquid
See label
Carrier Not Free
A synthetic peptide of human G protein alpha 13
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB, IHC-P
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.