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Anti-GDF15/MIC1 Antibody (Ponsegromab)

Catalog No.
F2030
Anti-GDF15/MIC1 Antibody (Ponsegromab)
Grouped product items
SizePriceStock Qty
100ug
Please inquire
Ship with 3-5 days
1mg
Please inquire
Ship with 3-5 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Ponsegromab (PF 06946860) is a potent, selective, humanized anti-GDF15 monoclonal antibody with anti-cachexia activity. Ponsegromab binds to GDF15 and prevents its binding to GFRAL, thereby blocking GDF15/GFRAL-mediated signaling. Ponsegromab can be used in cancer research.

Quality Control

Quality Control & DataSheet

View current batch:
 

M.Wt

145.4 kDa

Shipping

Dry ice

Cas No.

2368950-15-4

Storage

-80°C

Expiration Date

2 years

Form

Liquid

Concentration

See label

Reconstitution

For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.

Host

CHO

Alternative Names

PF-06946860, PF 06946860

Buffer System

100 mM Pro 20 mM Arg pH 5.0. No preservative!

Target Accession

Q99988

Reactivity

Human

Conjugation

Unconjugated

Clonality

Monoclonal

Purification

Protein A

Isotype

IgG1

Application

ELISA, FACS, Kinetics, Functional assay, Animal Model

Biological Activity

The purity of Anti-GDF15/MIC1 Antibody (Ponsegromab) is 99.55%, determined by SEC-HPLC.

Target

GDF15 / MIC1

Note

Please avoid freeze-thaw cycles.