Anti-FcRn (FCGRT & B2M) Antibody (Orilanolimab)
Catalog No.
F1703
Anti-FcRn (FCGRT & B2M) Antibody (Orilanolimab)
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Orilanolimab (SYNT001) is a humanized, deimmunized, FcRn-blocking monoclonal antibody. Orilanolimab blocks the interaction between FcRn and the Fc portion of the IgG molecule. Orilanolimab prevents IgG IC from activating FcRn-mediated adaptive immune function. Orilanolimab disrupts IgG homeostasis and innate and adaptive immunity.
Quality Control & DataSheet
- View current batch:
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Purity > 90% by SDS-PAGE and SEC-HPLC analyses.
- MSDS (Material Safety Data Sheet)
- Datasheet
144.6 kDa
Dry ice
2066544-85-0
-80°C
2 years
Liquid
See label
For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.
CHO
SYNT1001, ALXN1830
100 mM Pro 20 mM Arg pH 5.0. No preservative!
P55899
Human
Unconjugated
Monoclonal
Protein A
IgG1
ELISA, FACS, Kinetics, Functional assay, Animal Model
Immobilized FcRn (FCGRT) His+FcRn (B2M) at 2 ug/mL can bind Anti-FcRn (FCGRT & B2M) Reference Antibody (orilanolimab)
FcRn (FCGRT & B2M)
Please avoid freeze-thaw cycles.