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Anti-F3/Factor III/Tissue Factor/CD142 Antibody (Tisotumab vedotin)

Catalog No.
F1438
Anti-F3/Factor III/Tissue Factor/CD142 Antibody (Tisotumab vedotin)
Grouped product items
SizePriceStock Qty
100ug
$140.00
Ship with 3-5 days
1mg
$700.00
Ship with 3-5 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Tisotumab vedotin is an antibody-drug conjugate (ADC) targeting tissue factor (TF), which is covalently linked to a fully human monoclonal antibody to tissue factor (TF-011) and a microtubule disruptor Monomethyl Auristatin E (MMAE). Tisotumab vedotin has immunomodulatory and anti-tumor activities and can be used for the study of advanced or metastatic solid tumors such as cervical cancer.

Quality Control

Quality Control & DataSheet

View current batch:
 

M.Wt

144.66 kDa

Shipping

Dry ice

Cas No.

1418731-10-8

Storage

-80°C

Expiration Date

2 years

Form

Liquid

Concentration

See label

Reconstitution

For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.

Host

CHO

Alternative Names

TIVDAK, TF-011-vcMMAE, TF-011

Buffer System

100 mM Pro 20 mM Arg pH 5.0. No preservative!

Target Accession

P13726

Reactivity

Human

Conjugation

MMAE

Clonality

Monoclonal

Purification

Protein A

Isotype

IgG1

Application

ELISA, FACS, Kinetics, Functional assay, Animal Model

Biological Activity

The drug-to-antibody ratio (DAR) of the Anti-Tissue Factor /CD142 Reference Antibody (tisotumab vedotin) is 4.2.

Target

F3 / Factor III / Tissue Factor / CD142

Note

Please avoid freeze-thaw cycles.