Anti-Estrogen Receptor alpha Rabbit Monoclonal Antibody
Catalog No.
MA2517
Anti-Estrogen Receptor alpha Rabbit Monoclonal Antibody
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ER (estrogen receptor 1) a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ER regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery. Phosphorylation provides an important mechanism to regulate ER activity. ER is phosphorylated on multiple sites.
2099
ESR1; Era; Eralpha; Estrogen receptor; Estradiol receptor; ER-alpha; Estrogen receptor 1; NR3A1; ER; ESR; ESRA; Estrogen receptor alpha
Rabbit
Human, Mouse, Rat, Dog
Unconjugated
Calculated MW: 66 kDa; Observed MW: 60 kDa
Unmodified
IgG
Monoclonal Antibody
AP-17F7E9
Liquid
See label
Carrier Free
A synthesized peptide derived from human ER alpha
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IHC-P, ICC/IF, FC, ChIP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.