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Anti-ERBB3/ HER3 Antibody (Patritumab deruxtecan)

Catalog No.
F1567
Anti-ERBB3/ HER3 Antibody (Patritumab deruxtecan)
Grouped product items
SizePriceStock Qty
100ug
Please inquire
Ship with 3-5 days
1mg
Please inquire
Ship with 3-5 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Patritumab deruxtecan (HER3-DXd) is an antibody-active molecule conjugate (ADC) composed of the fully human anti-HER3 IgG1 monoclonal antibody patritumab linked to a topoisomerase I inhibitor payload via a tetrapeptide-based cleavable linker [1].

Quality Control

Quality Control & DataSheet

View current batch:
 

M.Wt

146.86 kDa

Shipping

Dry ice

Cas No.

2227102-46-5

Storage

-80°C

Expiration Date

2 years

Form

Liquid

Concentration

See label

Reconstitution

For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.

Host

CHO

Alternative Names

U3-1402

Buffer System

100 mM Pro 20 mM Arg pH 5.0. No preservative!

Target Accession

P21860

Reactivity

Human

Conjugation

Dxd

Clonality

Monoclonal

Purification

Protein A

Isotype

IgG1

Application

ELISA, FACS, Kinetics, Functional assay, Animal Model

Biological Activity

The drug-to-antibody ratio (DAR) of the Anti-ERBB3/ HER3 Reference Antibody (Patritumab deruxtecan) is 8.0.

Target

ERBB3 / HER3

Note

Please avoid freeze-thaw cycles.