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Anti-ERBB1/EGFR/HER1 Antibody (Serclutamab talirine)

Catalog No.
F1553
Anti-ERBB1/EGFR/HER1 Antibody (Serclutamab talirine)
Grouped product items
SizePriceStock Qty
100ug
Please inquire
Ship with 3-5 days
1mg
Please inquire
Ship with 3-5 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Serclutamab Talirine (ABBV-321) is an antibody-drug conjugate (ADC) consisting of a humanized immunoglobulin G1 anti-EGFR monoclonal antibody conjugated to a pyrrolobenzodiazepine (PBD) dimer via a maleimidocaproyl-valine-alanine linker. Serclamab Talirine has the potential to be used for the treatment of advanced solid tumors associated with overexpression of epidermal growth factor receptor (EGFR) or its ligands.

Quality Control

Quality Control & DataSheet

View current batch:
 

M.Wt

144.9 kDa

Shipping

Dry ice

Cas No.

2140174-56-5

Storage

-80°C

Expiration Date

2 years

Form

Liquid

Concentration

See label

Reconstitution

For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.

Host

CHO

Alternative Names

ABBV-321, PR1594407

Buffer System

100 mM Pro 20 mM Arg pH 5.0. No preservative!

Target Accession

P00533

Reactivity

Human,Mouse,Cynomolgus

Conjugation

PBD

Clonality

Monoclonal

Purification

Protein A

Isotype

IgG1

Application

ELISA, FACS, Kinetics, Functional assay, Animal Model

Biological Activity

Immobilized EGFR chis at 2 ug/mL can bind Serclutamab talirine with the EC50 of 0.02557 ug/mL.

Target

ERBB1 / EGFR / HER1

Note

Please avoid freeze-thaw cycles.