Anti-ERBB1/EGFR/HER1 Antibody (Serclutamab talirine)
Catalog No.
F1553
Anti-ERBB1/EGFR/HER1 Antibody (Serclutamab talirine)
Featured Products
Serclutamab Talirine (ABBV-321) is an antibody-drug conjugate (ADC) consisting of a humanized immunoglobulin G1 anti-EGFR monoclonal antibody conjugated to a pyrrolobenzodiazepine (PBD) dimer via a maleimidocaproyl-valine-alanine linker. Serclamab Talirine has the potential to be used for the treatment of advanced solid tumors associated with overexpression of epidermal growth factor receptor (EGFR) or its ligands.
144.9 kDa
Dry ice
2140174-56-5
-80°C
2 years
Liquid
See label
For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.
CHO
ABBV-321, PR1594407
100 mM Pro 20 mM Arg pH 5.0. No preservative!
P00533
Human,Mouse,Cynomolgus
PBD
Monoclonal
Protein A
IgG1
ELISA, FACS, Kinetics, Functional assay, Animal Model
Immobilized EGFR chis at 2 ug/mL can bind Serclutamab talirine with the EC50 of 0.02557 ug/mL.
ERBB1 / EGFR / HER1
Please avoid freeze-thaw cycles.