Anti-eIF4E Rabbit Monoclonal Antibody
Catalog No.
MA2422
Anti-eIF4E Rabbit Monoclonal Antibody
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eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types.
1977
EIF4E; EIF4EL1; EIF4F; Eukaryotic translation initiation factor 4E; eIF-4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding protein
Rabbit
Human
Unconjugated
Unmodified
IgG
Monoclonal Antibody
AP-19C2E12
Liquid
See label
Carrier Not Free
A synthesized peptide derived from human eIF4E
Affinity Purified
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
IHC-P
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.