Anti-EGFR (L858R mutation) Rabbit Monoclonal Antibody
Catalog No.
MA2392
Anti-EGFR (L858R mutation) Rabbit Monoclonal Antibody
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EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.
1956
EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
Rabbit
Human
Unconjugated
Calculated MW: 134 kDa; Observed MW: 175 kDa
Unmodified
IgG
Monoclonal Antibody
AP-13E3F5
Liquid
See label
Carrier Free
A synthesized peptide derived from human EGFR(L858R mutation)
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IHC-P, ICC/IF
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.