Anti-DR5 Rabbit Monoclonal Antibody
Catalog No.
MA2335
Anti-DR5 Rabbit Monoclonal Antibody
Featured Products
Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:10549288). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis
8795
TNFRSF10B; DR5, KILLER, TRAILR2, TRICK2, ZTNFR9; UNQ160/PRO186; CD262; Death receptor 5; Tumor necrosis factor receptor superfamily member 10B; NF-related apoptosis-inducing ligand receptor 2 (TRAIL receptor 2; TRAIL-R2)
Rabbit
Human
Unconjugated
Unmodified
IgG
Monoclonal Antibody
AP-20C11H5
Liquid
See label
Carrier Not Free
A synthesized peptide derived from human DR5
Affinity Purified
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
IHC-P
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.