Anti-DGCR8 Rabbit Monoclonal Antibody
Catalog No.
MA2264
Anti-DGCR8 Rabbit Monoclonal Antibody
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Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs DROSHA to cleave 11 bp away form the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs.
54487
DGCR8; DGCRK6; Gy1; C22orf12; D16Wis2; pasha
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 86 kDa; Observed MW: 120 kDa
Unmodified
IgG
Monoclonal Antibody
AP-15D10B11
Liquid
See label
Carrier Not Free
Recombinant protein of human DGCR8
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB, ICC/IF, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.