Anti-Daxx Rabbit Monoclonal Antibody
Catalog No.
MA2216
Anti-Daxx Rabbit Monoclonal Antibody
Featured Products
Acts as an adapter protein in a MDM2-DAXX-USP7 complex by regulating the RING-finger E3 ligase MDM2 ubiquitination activity. Under non-stress condition, in association with the deubiquitinating USP7, prevents MDM2 self-ubiquitination and enhances the intrinsic E3 ligase activity of MDM2 towards TP53, thereby promoting TP53 ubiquitination and subsequent proteasomal degradation. Upon DNA damage, its association with MDM2 and USP7 is disrupted.
1616
DAXX; BING2; DAP6; Death domain-associated protein 6; Daxx; hDaxx; ETS1-associated protein 1; EAP1; Fas death domain-associated protein
Rabbit
Human
Unconjugated
Calculated MW: 81 kDa; Observed MW: 110 kDa
Unmodified
IgG
Monoclonal Antibody
AP-8D11D9
Liquid
See label
Carrier Not Free
A synthetic peptide of human Daxx
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB, ICC/IF
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.